Is there a particular probiotic that is better for anxiety and depression?

The gut-brain axis refers to the bidirectional communication network between the central and autonomic nervous systems and the intestines. Gut-brain communications are mediated by the immune system, endocrine (hormone) connections such as the hypothalamic-pituitary-adrenal (HPA) axis, and neural pathways involving the enteric nervous system and vegas nerve.  The gut-brain axis is now thought to be critical in our understanding and treatment of depression and anxiety, and as clinical trials validating these concepts have begun to emerge in the last decade, a new class of probiotics also emerged – the so-called psychobiotics, or psychomicrobiotics – which hold significant promise for new, nontoxic treatment of psychiatric disorders.

Target gb-X by Klaire Labs with Ecologic BARRIER is a unique 9-strain probiotic blend formulated to support positive mood and address those with depression and anxiety. This shelf stable, 5 billion CFU probiotic was specifically designed to influence the gut-brain axis through defined mechanisms. Preclinical and human RCT trials have demonstrated that this probiotic formula specifically acts on the gut-brain axis through strengthening gut barrier function, decreasing inflammatory cytokines and proteins such as lipopolysaccharide (LPS) and zonulin endotoxins, encouraging the production of neuroprotective metabolites, and a marked reduction in transcription of hippocampal genes related to HPA dysregulation.

The gut-brain axis is a fascinating field of research, and Klaire Labs is on the front lines of innovative probiotic formulation to address such concerns.  Thus, Target-GBX would be a great choice for those with depression and anxiety and due to is mechanisms of restoring tight-junction integrity and protecting of intestinal barrier function, it has a broad range of applications including those with increased intestinal hyperpermeability (leaky gut) and HPA axis dysregulation or adrenal fatigue.

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